NCT00473187

Effects of GH on Body Proportions and Final Height in X-Linked Hypophosphatemic Rickets

Effects of Growth Hormone Treatment on Body Proportions and Final Height Among Small Children With X-Linked Hypophosphatemic Rickets

• Status: Unknown
• Phase: Phase 1
• Study type: Interventional
• Enrollment: —
• Sponsor: University of Rostock · Academic / Other
• Sex: All
• Age: 3 Years – 10 Years
• Healthy volunteers: Not accepted

Summary

X-linked hypophosphatemic rickets (XLH) is characterized by rickets, disproportionate short stature, impaired renal phosphate reabsorption and vitamin D metabolism. Despite oral phosphate and vitamin D treatment, most children with XLH demonstrate reduced adult height. The main objective of the study is to determine the beneficial effects of recombinant human growth hormone (rhGH) therapy on body proportions after 36 month in these patients. Secondary objective is to monitor side effects of the therapy.

Conditions

• Hypophosphatemic Rickets
• Growth Disorders
• Somatropin Therapy

Interventions

Type	Name	Description
DRUG	somatropin

Timeline

• Start date: 2004-08-01
• Completion: 2009-08-01
• First posted: 2007-05-14
• Last updated: 2007-05-14

Locations

1 site across 1 country: Germany