NCT00463515

Evaluation of Carboplatin Plus Gemcitabine Followed by Concomitant Chemoradiation for Non-resectable Stage III NSCLC

A Multicenter Phase II Study of Carboplatin Plus Gemcitabine Followed by Concomitant Chemoradiation in Patients With Non-resectable Stage III Non-Small-Cell-Lung Cancer

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 77 (planned)
• Sponsor: University Hospital, Antwerp · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to evaluate whether by combining a carboplatin-gemcitabine based induction chemotherapy with weekly cisplatin during standard thoracic radiotherapy it is possible to obtain optimal efficacy with minimal toxicity. Patients will be treated with 3 cycles of induction chemotherapy, unless there is the occurrence of early intrathoracic progression of disease. The induction chemotherapy is then to be followed by chemo-radiotherapy.

Conditions

• Non-Small-Cell-Lung Cancer

Interventions

Type	Name	Description
DRUG	carboplatin/gemcitabine
PROCEDURE	cisplatin/radiation therapy

Timeline

• Start date: 2003-01-01
• Primary completion: 2006-11-01
• Completion: 2006-11-01
• First posted: 2007-04-20
• Last updated: 2013-07-12

Locations

3 sites across 1 country: Belgium