NCT00463281

CT Based Definition of a Tissue Window for Acute Stroke Thrombolysis

Observational Study of Multimodal CT in Acute Ischemic Stroke to Define a Tissue Window for Thrombolysis

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: Technische Universität Dresden · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Aim of this study is to define a CT-based "tissue window" for stroke thrombolysis. Our primary hypothesis is that 1. patients with a "tissue window" (favourable non-contrast CT (NCCT) scan and an intracranial occlusion on CT angiography (CTA) or perfusion-CT-mismatch" (area of reduced cerebral blood flow (CBF) \> area of reduced cerebral blood volume (CBV)) represent a significant proportion (\> 20%)of acute stroke patients and therefore are an important target group for future interventional studies 2. patients with a "tissue window" suffer an unfavourable outcome (\> 50 % mRS =\>4 at 3 months)if the occluded artery was not recanalized.

Conditions

• Stroke

Timeline

• Start date: 2007-01-01
• Primary completion: 2008-01-01
• Completion: 2009-01-01
• First posted: 2007-04-20
• Last updated: 2009-05-14

Locations

1 site across 1 country: Germany