NCT00456755

Herbal Treatment for Perennial Allergic Rhinitis

A Herbal Formula (SBL) for the Treatment of Perennial Allergic Rhinitis: A Randomized, Double-blind, Placebo-controlled Clinical Trial

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 126 (actual)
• Sponsor: Chinese University of Hong Kong · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Allergic rhinitis(AR) is one of the most common allergic disorders throughout the world.The conventional therapies are effective in alleviating symptoms but the efficacy are limited and not persistent. Furthermonre, the cost and side-effect are known defects. A classical Chinese herbal formula, has been used for AR for centries. Our study purpose is to evaluate the clinical efficacy and safety of this formula verus placebo in perennial allergic rhinitis (PAR). Hypothesis: the classical herbal formula would improve the symptoms of PAR patients and change some immunological parameters in the peripheral blood when comparing with the placebo.

Detailed description

It is a randomized, double-blind, placebo-controlled trial.

Conditions

• Perennial Allergic Rhinitis

Interventions

Type	Name	Description
DRUG	Shi-Bi-Lin	4 weeks of treatment, dose of 1 g (two capsules), twice daily
OTHER	Placebo	4 weeks of colormatched placebo capsules, dose of 1 g (two capsules), twice daily

Timeline

• Start date: 2004-03-01
• Primary completion: 2006-04-01
• Completion: 2006-04-01
• First posted: 2007-04-05
• Last updated: 2010-01-06
• Results posted: 2010-01-06

Locations

2 sites across 1 country: Hong Kong