NCT00453778

A Study To Investigate The Effect Of Inhaled Fluticasone Propionate On The Bronchial Responsiveness To Leukotriene D4 In Asthmatics Patients

A Study to Investigate the Effect of Inhaled Fluticasone Propionate on the Bronchial Responsiveness to Leukotriene D4 in Asthmatics Patients

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 14 (planned)
• Sponsor: GlaxoSmithKline · Industry
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

Investigate if asthmatics treated with FLIXOTIDE (FP) 500 mcg BID during 14 days get reduced bronchial reactivity after inhalation of Leukotriene D4. Two 14 days treatment periods where patients received FP 500 MCG BID and placebo. Washout at least 21 days between treatments. Bronchial challenge with methacholine and Leukotriene D4 were performed before the start of each treatment period and on treatment days 13 and 14 respectively.

Conditions

• Asthma
• Mild Asthma

Interventions

Type	Name	Description
DRUG	FLIXOTIDE Diskus 500 mcg (Fluticasone Propionate)

Timeline

• Start date: 2002-11-01
• Primary completion: 2004-05-01
• Completion: 2004-05-01
• First posted: 2007-03-29
• Last updated: 2013-02-12