Trials / Completed
CompletedNCT00451360
Chondromodulating Effect of Diacerein in Osteoarthritis of the Hip
Evaluation of the CHOndromodulating Effect of DIAcerein in Osteoarthritis of the Hip. ECHODIAH.
- Status
- Completed
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 500 (planned)
- Sponsor
- Laboratoires NEGMA · Industry
- Sex
- All
- Age
- 50 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
We carried out a 3 years, randomized, double-blind, placebo-controlled, multicenter clinical trial in patients with hip osteoarthritis in order to: * evaluate the ability of diacerein, an interleukin-1β inhibitor, to slow the progressive decrease in joint space width observed in patients with hip osteoarthritis * to investigate the potential structure-modifying effect of diacerein in patients with hip osteoarthritis This study compare also after ten years the percentage of patients in each treatment group who require a hip replacement surgery
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | diacerein |
Timeline
- Start date
- 1993-03-01
- Completion
- 1997-04-01
- First posted
- 2007-03-23
- Last updated
- 2008-07-25
Locations
25 sites across 1 country: France
Source: ClinicalTrials.gov record NCT00451360. Inclusion in this directory is not an endorsement.