NCT00448513

Effects of Tea Catechin Extracts on Oxidative Damage

Effects of Tea Catechin Extracts on the Frequency Changes of Micronuclei in Peripheral Lymphocytes in Late Middle Aged Healthy Volunteers

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: University of Shizuoka · Academic / Other
• Sex: All
• Age: 40 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to clarify the effects of tea catechin extracts on the frequency changes of micronuclei in peripheral lymphocytes compared with other oxidative stress markers in late middle aged healthy volunteers

Detailed description

Experimental studies have revealed that tea catechin extracts induce preventive effects on oxidative stress, but there have been few clinical trials conducted to verify the effects. Also, there have been few clinical markers indicating oxidative damage, and therefore, more accurate and reliable markers have been expected. The study is designed for evaluating the effects of tea catechin extracts on the frequency changes of micronuclei in peripheral lymphocytes as the indicator of oxidative damage, compared with other oxidative stress markers in late middle aged healthy volunteers.

Conditions

• Healthy

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	catechin extracts	comparison with placebo

Timeline

• Start date: 2007-06-01
• Primary completion: 2009-08-01
• Completion: 2012-04-01
• First posted: 2007-03-19
• Last updated: 2013-07-16

Locations

1 site across 1 country: Japan