NCT00446277

Corneal Endothelial Cell Loss in Diabetes Type II During Cataract Surgery

• Status: Suspended
• Phase: —
• Study type: Observational
• Enrollment: 30 (estimated)
• Sponsor: Frederiksberg University Hospital · Academic / Other
• Sex: All
• Age: 50 Years
• Healthy volunteers: Not accepted

Summary

The aim of the present study is to evaluate changes in the morphology and function of the corneal endothelium before and after cataract surgery in patients with diabetes type II. Also to explain if determination of HgbA1c in diabetics is a predictor for the changes in morphology and function.

Detailed description

Thirty patients with Diabetes type II and thirty non-diabetes patients scheduled to cataract surgery (phacoemulsification with intraocular lens implantation) were invited to participate in the study. Preoperatively, all patients had a full eye examination and 3 endothelial cell photos were taken. Three months postoperatively the patients were called for a re-examination including 3 endothelial cell photos. The function of the cornea is dependent of the number and morphology of the endothelial cells, and even small traumas like cataract surgery may disrupt the cornea integrity leading to corneal haze and blur. Diabetics may be more vulnerable to corneal stress.

Conditions

• Diabetes Mellitus

Interventions

Type	Name	Description
PROCEDURE	cataract surgery

Timeline

• Start date: 2007-01-01
• Primary completion: 2007-06-01
• Completion: 2007-06-01
• First posted: 2007-03-12
• Last updated: 2008-05-12

Locations

1 site across 1 country: Denmark