NCT00442338

Study of MK-0476 in Adult Patients With Acute Asthma (0476-334)

MK-476 IV Formulation Phase III Open Label Exploratory Comparative Study - Acute Exacerbations of Asthma -

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 91 (actual)
• Sponsor: Organon and Co · Industry
• Sex: All
• Age: 15 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The study estimates the efficacy and safety of MK0476 and aminophylline intravenous administration in adult participants with acute asthma.

Conditions

• Asthma

Interventions

Type	Name	Description
DRUG	montelukast sodium	Montelukast 7 mg single injection (IV bolus administration) over 2-3 minutes
DRUG	montelukast sodium	Montelukast 14 mg single injection (IV bolus administration) over 5 minutes
DRUG	aminophylline hydrate	Aminophylline 250 mg IV drip infusion over 60 minutes

Timeline

• Start date: 2007-03-01
• Primary completion: 2007-08-01
• Completion: 2007-08-01
• First posted: 2007-03-01
• Last updated: 2022-02-02
• Results posted: 2009-07-14