Clinical Trials Directory

Trials / Terminated

TerminatedNCT00442104

Open-label Extension to Protocol 1042-0500

An Open-label Clinical Study to Evaluate the Safety and Antiepileptic Activity of Ganaxolone in Treatment of Patients Diagnosed With Infantile Spasms.

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
54 (actual)
Sponsor
Marinus Pharmaceuticals · Industry
Sex
All
Age
4 Months – 24 Months
Healthy volunteers
Not accepted

Summary

To allow open-label extension to patients who have completed Protocol 1042-0500

Detailed description

Patient should have completed all scheduled clinical study visits in the double blind, controlled trial (Protocol 1042-0500) and have been deemed eligible (had a response to treatment) by the Investigator. Male or female, with a diagnosis of IS with a video EEG (vEEG) recording confirming the diagnosis. There will be a total of 14 visits over 99(+or-1)week. A 24-hr vEEG is only required if the subject has been spasm-free for more than 24-hrs.

Conditions

Interventions

TypeNameDescription
DRUGGanaxolone

Timeline

Start date
2007-01-01
Primary completion
2009-03-01
Completion
2009-03-01
First posted
2007-03-01
Last updated
2024-05-28
Results posted
2023-06-02

Locations

14 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT00442104. Inclusion in this directory is not an endorsement.

Open-label Extension to Protocol 1042-0500 (NCT00442104) · Clinical Trials Directory