NCT00440570

A Study of Therapeutic Amplitude-modulated Electromagnetic Fields in Advanced Tumors

Treatment of Advanced Cancer With Amplitude-modulated Electromagnetic Fields of Low Intensity by Means of an Intrabuccal Probe

• Status: Completed
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 2 (planned)
• Sponsor: Pasche, Boris, M.D. · Individual
• Sex: All
• Age: 18 Years – 95 Years
• Healthy volunteers: Accepted

Summary

In vitro studies suggest that low levels of amplitude-modulated electromagnetic fields may modify cell growth. We have identified specific frequencies that may block cancer cell growth. We have developed a device delivering low levels of amplitude-modulated electromagnetic fields. The device is connected to a spoon-like coupler, which is placed in the patient's mouth during treatment. We will conduct a feasibility study consisting of three daily ambulatory treatments until disease progression.

Detailed description

Background: In vitro studies suggest that low levels of amplitude-modulated electromagnetic fields may modify cell growth. We have identified specific frequencies that may block cancer cell growth. We have developed a portable and programmable device delivering low levels of amplitude-modulated electromagnetic fields. The device is connected to a spoon-like coupler, which is placed in the patient's mouth during treatment. Methods: We will conducted a feasibility study consisting of three daily treatments. All patients with advanced solid tumors and measurable disease will be eligible, irrespective of prior treatments. Patients will be assessed with laboratory exams (complete blood count, comprehensive profile, tumor markers), imaging studies every other month for the first six months, every third month thereafter.

Conditions

• Cancer
• Brain Tumor

Interventions

Type	Name	Description
DEVICE	Low levels of amplitude-modulated electromagnetic fields
DEVICE	Emitter of low levels of amplitude-modulated electromagnetic fields

Timeline

• Start date: 2004-10-01
• Primary completion: 2006-09-01
• Completion: 2007-12-01
• First posted: 2007-02-27
• Last updated: 2011-06-29

Locations

1 site across 1 country: Switzerland