Trials / Terminated
TerminatedNCT00440180
Aromatase Inhibitors in the Treatment of Male Infertility
The Role of Aromatase Inhibitors in the Treatment of Infertility in Obese Male
- Status
- Terminated
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 20 (actual)
- Sponsor
- University of Utah · Academic / Other
- Sex
- Male
- Age
- 16 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
Obesity is associated with an increase in blood levels of estrogen. Estrogen or "female hormone" is believed to have a negative effect on sperm production. Aromatase inhibitors such as anastrozole work to decrease the production of estrogen and increase testosterone in the body. By decreasing the level of estrogen, sperm production should improve. In this study, the investigators will try to determine the benefit of anastrozole in obese men and follow pregnancy outcomes.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Anastrozole | 1 mg qd for 4 months |
| DRUG | Placebo | Placebo Comparator |
Timeline
- Start date
- 2007-03-01
- Primary completion
- 2014-06-01
- Completion
- 2014-06-01
- First posted
- 2007-02-26
- Last updated
- 2016-04-06
- Results posted
- 2016-03-07
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00440180. Inclusion in this directory is not an endorsement.