NCT00437775

ACEIs and ARBs Treatment in Diabetic Patients -Drug Interactions and Adverse Drug Effects

Angiotensin Converting Enzyme Inhibitors & Angiotensin Receptor Blocker in the Treatment of Type 2 Diabetic Patients Adverse Drug Effects and Drug Interactions- a Survey in an Internal Medicine Department.

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 300 (planned)
• Sponsor: Assaf-Harofeh Medical Center · Other Government
• Sex: All
• Age: 40 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

Proteinuria is an expression of diabetic nephropaty in type 1 and type 2 patients. Hypertenshion treatment and decreasing urine protein excretion, slow down renal deterioration. Treating diabetic ,hypertensive patients with Angiotensin Converting Enzyme inhibitors (ACEi), Angiotensin receptor blockers (ARBs)is common practice. The aim of our work is to examine 1.The prevalence of ACE and ARB treatment in diabetic patients with or without hypertension.2. Adverse drug reactions of ACEi and ARBs alone or in combination.

Detailed description

The study group- men and women with diabetes mellitus type 2,who were hospitalized in the department of internal medicine in Assaf- Harofeh Medical Center. During hospitalization, data regarding the clinical history,chronic diseases and drugs were collected from the medical files. Blood tests results were recorded during hospitalization .The patients were asked about adverse drug effects.

Conditions

• Diabetes Mellitus Type 2

Timeline

• Start date: 2007-01-01
• Completion: 2007-03-01
• First posted: 2007-02-21
• Last updated: 2007-02-21

Locations

1 site across 1 country: Israel