Trials / Completed
CompletedNCT00435539
A Study to Compare Multiple Doses Intravitreal Microplasmin for Treatment of Patients With Vitreomacular Traction (MIVI-IIt)
A Randomized, Sham-Injection Controlled, Double-Masked, Ascending-Dose, Dose-Range-Finding Trial of Microplasmin Intravitreal Injection for Non-Surgical Posterior Vitreous Detachment (PVD) Induction for Treatment of Vitreomacular Traction (VMT).
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 60 (actual)
- Sponsor
- ThromboGenics · Industry
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
A multicenter study to compare multiple doses of intravitreal microplasmin for non-surgical PVD induction for treatment of patients with vitreomacular traction.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | ocriplasmin | Intravitreal injection of ocriplasmin solution containing 75µg of ocriplasmin. |
| DRUG | ocriplasmin | Intravitreal injection of ocriplasmin solution containing 125µg of ocriplasmin with up to 2 additional (open label) 125µg ocriplasmin injection at 1 month interval. |
| DRUG | Sham Comparator | Intravitreal sham injection |
Timeline
- Start date
- 2007-02-01
- Primary completion
- 2009-01-01
- Completion
- 2009-02-01
- First posted
- 2007-02-15
- Last updated
- 2014-12-17
- Results posted
- 2013-09-13
Locations
4 sites across 2 countries: Belgium, Germany
Source: ClinicalTrials.gov record NCT00435539. Inclusion in this directory is not an endorsement.