NCT00432952

Acute Single Meal Effects of Trout on Cardiovascular Risk Markers and Plasma Proteome

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 6 (planned)
• Sponsor: University of Copenhagen · Academic / Other
• Sex: Male
• Age: 40 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The acute effects of farmed rainbow trout, fed by various feeds versus a control meal with poultry meat on cardiovascular risk markers and plasma protein expression are investigated. The hypotheses of the study are that if the feed are changed from a marine origin to primarily a vegetable origin the content of long chain n-3 poly unsaturated fatty acids (n-3 PUFA) will decrease in the meat and thus possibly result in a decreased effect on health. Furthermore, the feed of the trouts are also expected to give rise to differences in the human plasma protein profile and fatty acid composition after consumption, which could be associated with physiological effects.

Detailed description

In a controlled, single blinded human single meal study the acute effects of farmed rainbow trout, fed by various feeds versus a control meal with poultry meat on cardiovascular risk markers and plasma protein expression are investigated. 6 healthy men, age 40-70, will be randomized to trout fed on only vegetable, only marine and a mix of different compositions of vegetable and marine feeds. Outcome variables are blood pressure, pulse wave analyse, pulse wave velocity, plasma protein profile, and plasma triglycerides. The hypotheses of the study are that if the feed are changed from a marine origin to primarily a vegetable origin the content of long chain n-3 poly unsaturated fatty acids (n-3 PUFA) will decrease in the meat and thus possibly result in a decreased effect on health. Furthermore, the feed of the trouts are also expected to give rise to differences in the human plasma protein profile and fatty acid composition after consumption, which could be associated with physiological effects.

Conditions

• Cardiovascular Diseases
• Metabolic Syndrome

Interventions

Type	Name	Description
BEHAVIORAL	Intake of rainbow trout from different feeding conditions versus a control poultry meal

Timeline

• Start date: 2007-01-01
• Primary completion: 2007-03-01
• Completion: 2009-01-01
• First posted: 2007-02-08
• Last updated: 2008-08-13

Locations

1 site across 1 country: Denmark