NCT00431743

Fluid Infusion During Breast Surgery

Phase 4 Study of Fluid Infusion During Breast Surgery.

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 32 (estimated)
• Sponsor: Rigshospitalet, Denmark · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The investigators want to investigate the effects of two different kinds of fluid infusions given during varicose vein surgery. Both types of fluid are regularly given during surgery, and the investigators want to compare their respective effects on balance, nausea/vomiting and orthostatic function after surgery. The investigators' hypothesis is that using a colloid solution will improve orthostatic function, balance, nausea/vomiting and reduce hospital stay.

Detailed description

The optimal amount and type of fluid given during surgery has not been defined. It has been agreed that hypovolemia must be avoided, but at the same time it has been agreed that fluid excess is harmful for organ function.When distributing fluids it is usually either crystalloids og colloids which are given. The effects of the two types of fluid have not been compared. Our hypothesis is that using a colloid (HES 130/0,4) will improve orthostatic function, nausea/vomiting and shorten hospital stay, compared to using a crystalloid (Lactated Ringer's solution).The amount of fluid the patient receives, will be individually tailored by monitoring SV using esophageal Doppler technique during surgery.

Conditions

• Breast Surgery

Interventions

Type	Name	Description
DRUG	Hydroxyethylstarch 130/0,4
DRUG	Lactated Ringer's solution

Timeline

• Start date: 2009-04-01
• Primary completion: 2009-09-01
• Completion: 2009-09-01
• First posted: 2007-02-06
• Last updated: 2009-03-03

Locations

1 site across 1 country: Denmark