Trials / Terminated
TerminatedNCT00420862
The DANTE Trial. A Randomized Study on Lung Cancer Screening With Low-Dose Spiral Computed Tomography
- Status
- Terminated
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 2,400 (planned)
- Sponsor
- Istituto Clinico Humanitas · Academic / Other
- Sex
- Male
- Age
- 60 Years – 74 Years
- Healthy volunteers
- Accepted
Summary
High survival rates have been reported for screen-detected Stage I lung cancer patients, but there are concerns about the potential biases of uncontrolled studies. DANTE is a prospective randomized controlled trial exploring the effects of screening with LDCT on lung-cancer-specific mortality, and on the prevalence and incidence rates of lung cancer, stage distribution and resectability rates in a selected high-risk population. The prevalence of a set of biomarkers in sputum and blood samples is also being determined.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Spiral Computed Tomography |
Timeline
- Start date
- 2001-06-01
- Completion
- 2010-02-01
- First posted
- 2007-01-11
- Last updated
- 2007-01-11
Locations
1 site across 1 country: Italy
Source: ClinicalTrials.gov record NCT00420862. Inclusion in this directory is not an endorsement.