NCT00419627

Proteomic Analysis of HLA Complex in Solid Cancers: Breast, Ovary, Colon, Rectum, Stomach, and Pancreas

Proteomic Analysis of Serology and Peptides Presented on the HLA Complex of Breast, Ovarian, Colon, Rectal, Gastric and Pancreatic Adenocarcinoma.

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 160 (planned)
• Sponsor: Hillel Yaffe Medical Center · Other Government
• Sex: All
• Age: —
• Healthy volunteers: —

Summary

The purpose of this study is to evaluate the presence of proteins in solid tumors which may lead to an immune response

Detailed description

The main objective of the study is to evaluate which proteins are presented by the HLA complex of solid tumors. Secondary objectives include to evaluate whether an immune response specific to these proteins has actually been provoked and whether there is a similar immune response following recurrence. Real specimens will be evaluated using PCR and mass spectrometry.

Conditions

• Colorectal Neoplasms
• Stomach Neoplasms
• Pancreatic Neoplasms
• Breast Neoplasms
• Ovarian Cancer

Timeline

• Start date: 2007-02-01
• First posted: 2007-01-08
• Last updated: 2007-01-08

Locations

1 site across 1 country: Israel