Trials / Completed
CompletedNCT00416299
Prognostic Value of New Cardiac Biomarkers in Elderly Patients Undergoing Cardiac Surgery
Observational Cohort Study on the Prognostic Value of New Cardiac Biomarkers in Elderly Patients Undergoing Cardiac Surgery
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 100 (actual)
- Sponsor
- Klinikum Ludwigshafen · Academic / Other
- Sex
- All
- Age
- 75 Years
- Healthy volunteers
- Not accepted
Summary
To evaluate the use of new cardiac biomarker for the prediction of in-hospital cardiovascular complications in elderly patients undergoing elective cardiac surgery.
Detailed description
Plasma N-terminal pro-brain natriuretic peptide (NT-proBNP, cardiac troponin T (cTnT), pregnancy-associated plasma protein A (PAPP-A), ischemia-modified albumin (IMA), myeloperoxidase (MPO), metalloproteinase (MMP) soluble CD 40 ligand (sCD40L), and inflammatory cytokine levels will be measured in 100 elderly patients undergoing elective cardiac surgery with cardiopulmonary bypass before induction of anesthesia and 12 h, 24 h, and 48 h after surgery. Optimum discriminators for prediction of postoperative cardiovascular complications wil be determined by the use of receiver operating characteristics (ROC) curves analyses.
Conditions
Timeline
- Start date
- 2007-05-01
- Completion
- 2007-08-01
- First posted
- 2006-12-27
- Last updated
- 2009-01-30
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT00416299. Inclusion in this directory is not an endorsement.