NCT00406679

Analgesic Efficacy, Safety and Tolerability of Two Paracetamol-containing Solutions in Post-Surgical Dental Pain

Single-Dose Comparison of the Analgesic Efficacy, Safety and Tolerability of Two Paracetamol 1%-Containing Solutions and Placebo in a Post-Surgical Dental Pain Model

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 135 (actual)
• Sponsor: Baxter Healthcare Corporation · Industry
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The aim of the study is to evaluate the therapeutic efficacy and safety of two different paracetamol-containing solutions in postoperative dental pain. They will be compared to placebo (a dummy treatment which contains no active ingredient).

Conditions

• Pain, Postoperative

Interventions

Type	Name	Description
DRUG	Paracetamol (acetaminophen) solution experimental	1 gm IV
DRUG	paracetamol (acetaminophen) solution commercial	1 gm IV
DRUG	placebo	equivalent volume IV 0.9% sodium chloride (equivalent volume)

Timeline

• Start date: 2006-11-01
• Primary completion: 2007-10-01
• Completion: 2007-10-01
• First posted: 2006-12-04
• Last updated: 2011-08-11

Locations

2 sites across 1 country: United Kingdom