NCT00406146

Amodiaquine+Artesunate vs. Artemether-Lumefantrine for Uncomplicated Malaria in Ghanaian Children

• Status: Unknown
• Phase: Phase 3
• Study type: Interventional
• Enrollment: —
• Sponsor: University of Ghana Medical School · Academic / Other
• Sex: All
• Age: 6 Months – 14 Years
• Healthy volunteers: —

Summary

Artemisinin combination therapies (ACT) are currently recommended for malaria treatment. Artemether-lumefantrine(A-L) and Artesunate+amodiaquine (A+A) have been the most commonly adopted of the recommended ACT regimens. In Ghana, A+A is the current first-line antimalarial treatment in Ghana, but there has been 1 efficacy report of this regimen in Ghana till date. Moreover, the safety of repeated treatments with ACT has been little studied. This study aims to evaluate the efficacy of A+A vs. A-L, as well as the safety of repeated treatments of these regimens in a longitudinal trial in which recruited children will be followed up for 1 year.

Conditions

• Uncomplicated Malaria

Interventions

Type	Name	Description
DRUG	amodiaquine+artesunate/artemether-lumefantrine

Timeline

• Start date: 2004-10-01
• Completion: 2006-12-01
• First posted: 2006-12-04
• Last updated: 2006-12-04

Locations

1 site across 1 country: Ghana