NCT00404794

A Study to Compare Mycophenolate Mofetil and Tacrolimus in the Treatment of Membranous Lupus Nephritis

A Prospective Randomized Open-label Study to Compare Mycophenolate Mofetil and A Prospective Randomized Open-label Study to Compare Mycophenolate Mofetil and Corticosteroid With Tacrolimus and Corticosteroid as Immunosuppressive Treatment for Lupus Membranous Nephritis

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Hospital Authority, Hong Kong · Other Government
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: —

Summary

This is a prospective randomized open-label pilot study to compare mycophenolate mofetil in combination with corticosteroid treatment and tacrolimus in combination with corticosteroid treatment in membranous lupus nephritis. The change in urine protein excretion will be the primary outcome studied. The study duration will be 24 months for each patient.

Conditions

• Lupus Nephritis
• Glomerulonephritis, Membranous

Interventions

Type	Name	Description
DRUG	prednisolone and mycophenolate mofetil
DRUG	prednisolone and tacrolimus

Timeline

• Start date: 2005-11-01
• Completion: 2009-10-01
• First posted: 2006-11-29
• Last updated: 2013-10-23

Locations

1 site across 1 country: China