Clinical Trials Directory

Trials / Completed

CompletedNCT00404469

Effects of Peritendinous Corticosteroid Injections, Eccentric Training and Heavy Slow Resistance Training in Patellar Tendinopathy

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
39 (actual)
Sponsor
Bispebjerg Hospital · Academic / Other
Sex
Male
Age
18 Years – 55 Years
Healthy volunteers
Not accepted

Summary

We will investigate the effect of peritendinous corticosteroid injections, eccentric training and heavy resistance training in male patellar tendinopathy patients. The purpose is to compare the clinical effect of these three treatments in a randomised controlled trial. Also we wish to investigate the treatment mechanisms responsible for the effectiveness of the three treatments.

Detailed description

3 interventions groups as described above (n=13 in each group) 12 weeks intervention period. Clinical assessments before and after intervention: VAS, VISA, Tendon thickness, Doppler us activity. Before and after intervention tendon biopsies will be taken and analyzed for crosslinks and fibril diameter. Also tendon mechanical properties will be measured. Tendon and muscle structural properties will be measured with MRI. Treatment satisfaction will be stated after intervention period.

Conditions

Interventions

TypeNameDescription
PROCEDUREperitendinous corticosteroid injections1 ml of40mg/ml methylprednisolone acetate at 0 and 4 weeks. 2 week observational
PROCEDUREeccentric decline squat trainingeccentric decline unilateral squats performed twice daily. for 12 weeks
PROCEDUREheavy slow resistance trainingHeavy slow resistance training for knee extensors. 3/week. total of 12 weeks

Timeline

Start date
2006-03-01
Completion
2007-11-01
First posted
2006-11-28
Last updated
2008-05-22

Locations

1 site across 1 country: Denmark

Source: ClinicalTrials.gov record NCT00404469. Inclusion in this directory is not an endorsement.