NCT00404079

The Glucosamine-study: The Effect of Glucosamine in Treatment of Chronic Low Back Pain

Phase 4 Study of Glucosamine Sulphate in the Treatment for Chronic Low Back Pain Patients With Degenerative Lumbar MRI Findings

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 250 (actual)
• Sponsor: Ullevaal University Hospital · Academic / Other
• Sex: All
• Age: 25 Years
• Healthy volunteers: Accepted

Summary

Low back pain (LBP) is the most frequent cause of sick leave and disability pension, and degenerative and osteoarthritic (OA) changes is a significant cause of pain and disability. Some indications exist for symptomatic and possible cartilage-structurmodifying effect on knee- and hip-osteoarthritis with glucosamine sulphate (GS). The OA process in the lumbar spine is most likely to OA processes in knees and hips, hence GS could have comparable symptomatic and structural effect on lumbar OA. Study hypothesis: No difference in treatment effect exists between oral intake of GS- or placebo-capsules for patients' with chronic low back pain measured with Roland Morris Disability Questionnaire.

Conditions

• Low Back Pain

Interventions

Type	Name	Description
DRUG	Glucosamine sulphate	Oral intake of 1500 mg glucosamine sulfate(from Pharma Nord) daily for 6 months
DRUG	Placebo	Oral intake of 3 placebo capsules (similiar looking to the glucosamine sulfate capsules)daily for 6 months

Timeline

• Start date: 2006-12-01
• Primary completion: 2009-08-01
• Completion: 2010-11-01
• First posted: 2006-11-27
• Last updated: 2011-04-29
• Results posted: 2011-04-29

Locations

1 site across 1 country: Norway