NCT00402753

Ambulatory Physical Exercise Program in Hematopoietic Stem Cell Transplantation Recipients

Physical Exercise to Improve Physical Performance and Health Related Quality of Life in Hematopoietic Stem Cell Transplantation Recipients

• Status: Completed
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 128 (estimated)
• Sponsor: University of Zurich · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The proposed study in an inception cohort of patients with hematological malignancies treated with PBSCT is designed to evaluate the effects of a physical exercise intervention on muscular-skeletal, physical activity and quality of life outcomes.

Detailed description

Peripheral Stem Cell Transplantation is a frequently used therapy option to increase survival in hematological and lymphatic malignancies. These malignancies and their treatment are associated with numerous physical and psychological symptoms and severe side effects. Physical exercise has been proposed as a promising strategy for the treatment of some of these physical and psychological complaints, and various exercise interventions are currently available after cancer treatment. To date, promising preliminary results concerning exercise programs in PBSCT recipients were published with limited sample size populations. Results of musculoskeletal outcomes in PBSCT recipients after cancer treatment are lacking.

Conditions

• Hematopoietic Stem Cell Transplantation

Interventions

Type	Name	Description
BEHAVIORAL	Ambulatory Physical Exercise Program	supervised exercise, 2 x / week

Timeline

• Start date: 2005-01-01
• Primary completion: 2009-12-01
• Completion: 2009-12-01
• First posted: 2006-11-22
• Last updated: 2010-01-07

Locations

4 sites across 2 countries: Netherlands, Switzerland