Clinical Trials Directory

Trials / Completed

CompletedNCT00401323

Taxotere (Docetaxel) in 1st Line Treatment of Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

A Randomized Phase II-III Multicenter Trial of Docetaxel Plus Cisplatin and Docetaxel Plus 5-FU Versus Cisplatin Plus 5-FU in 1st Line Treatment of Patients With Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck.

Status
Completed
Phase
Phase 2 / Phase 3
Study type
Interventional
Enrollment
568 (actual)
Sponsor
Sanofi · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

The purpose of the study is to compare time to progression and overall survival after treatment with Taxotere plus cisplatin versus cisplatin plus 5-FU (PF treatment group) in the first line treatment of patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck.

Conditions

Interventions

TypeNameDescription
DRUGdocetaxel (XRP6976)
DRUGcisplatin
DRUG5-fluorouracil (5-FU)

Timeline

Start date
1998-01-01
Primary completion
2003-06-01
Completion
2003-06-01
First posted
2006-11-20
Last updated
2011-01-20

Locations

20 sites across 20 countries: United States, Argentina, Australia, Austria, Belgium, Brazil, Canada, France, Germany, Greece, Guadeloupe, Hungary, Israel, Italy, Reunion, Russia, South Africa, Spain, Switzerland, Uruguay

Source: ClinicalTrials.gov record NCT00401323. Inclusion in this directory is not an endorsement.