Clinical Trials Directory

Trials / Terminated

TerminatedNCT00401310

The Efficacy and Safety of MK0724 IV for Improvement of Neurological Damage and Recovery From Middle Cerebral Artery Ischemic Stroke (0724-018)

A Phase IIa Randomized, Double-Blind, Parallel-Groups, Placebo Controlled Clinical Trial to Study the Efficacy and Safety of MK0724 Intravenous Infusion on the Amelioration of Neurological Damage and Recovery From Middle Cerebral Artery Ischemic Stroke

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
150 (actual)
Sponsor
Merck Sharp & Dohme LLC · Industry
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Not accepted

Summary

The safety and efficacy of MK0724 will be assessed in patients with acute middle cerebral artery stroke using the Action Reach Arm Test (ARAT). This test allows measurement of a specific functional deficit and subsequent recovery correlating with the specific area of stroke in the brain.

Conditions

Interventions

TypeNameDescription
DRUGComparator: PlaceboPlacebo IV infusions 1hr/daily over 7 days.
DRUGComparator: MK0724MK0724 8 mg/kg/hr 1 hr/daily over 7 days.

Timeline

Start date
2007-07-01
Primary completion
2009-01-01
Completion
2009-01-01
First posted
2006-11-20
Last updated
2015-07-22

Source: ClinicalTrials.gov record NCT00401310. Inclusion in this directory is not an endorsement.