Trials / Completed
CompletedNCT00398502
Comparisons Of The Bioavailability And Pharmacodynamics Of Various Formulations Of MOA-728 In Subjects On Methadone
A Randomized, Open-label, 3-period Crossover Study to Determine the Relative Bioavailability of Two Oral Formulations of MOA-728 and to Compare the Pharmacodynamics of the Two Oral Formulations of MOA-728 and the Subcutaneous Formulation in Subjects on Stable Methadone Maintenance
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- —
- Sponsor
- Bausch Health Americas, Inc. · Industry
- Sex
- All
- Age
- 18 Years – 65 Years
- Healthy volunteers
- Not accepted
Summary
Primary: To determine the relative bioavailability of MOA-728, an investigational drug, administered orally in both the capsule and tablet formulations to methadone maintenance subjects.Secondary: To assess the pharmacodynamic effect of MOA-728 administered both orally and subcutaneously to methadone maintenance subjects using the oral-cecal transit time.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | MOA-728 |
Timeline
- Start date
- 2006-10-01
- Completion
- 2006-12-01
- First posted
- 2006-11-10
- Last updated
- 2019-11-25
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00398502. Inclusion in this directory is not an endorsement.