Clinical Trials Directory

Trials / Terminated

TerminatedNCT00396058

The Effect of Methylphenidate on Motor Learning in Stroke Patients

Methylphenidats Betydning for motoriskindlæring Hos Patienter Med Apopleksi

Status
Terminated
Phase
Phase 4
Study type
Interventional
Enrollment
13 (estimated)
Sponsor
University of Aarhus · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of the study is to determine whether methylphenidate facilitates so called short-term plasticity as measures with transcranial magnetic stimulation, in patients with stroke.

Detailed description

Stroke patients are to be examined with transcranial magnetic stimulation (TMS) before and after a short training session. TMS will be used to demonstrate changes in cortical excitability (motor threshold) and intracortical inhibition and facilitation. The effect of methylphenidate on baseline TMS measures will be evaluated as well as the effect on training induced changes in TMS measures (by comparing baseline and posttraining measures). The patients will be trained on two separate occasions, to compare the effect of Methylphenidate to placebo.

Conditions

Interventions

TypeNameDescription
DRUGMethylphenidate

Timeline

Start date
2006-11-01
Completion
2008-03-01
First posted
2006-11-06
Last updated
2008-03-27

Locations

2 sites across 1 country: Denmark

Source: ClinicalTrials.gov record NCT00396058. Inclusion in this directory is not an endorsement.