Clinical Trials Directory

Trials / Completed

CompletedNCT00394082

ABI-007 In Combination With Bevacizumab in Women With Metastatic Breast Cancer

A Phase II Trial of Weekly Administration of ABI-007 In Combination With Bevacizumab in Women With Metastatic Breast Cancer

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
50 (actual)
Sponsor
Celgene · Industry
Sex
Female
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the safety and tolerability of weekly ABI-007 in combination with bevacizumab. The evaluation of progression-free survival of weekly ABI-007 in combination with bevacizumab for patients with previously untreated advanced/metastatic breast cancer.

Conditions

Interventions

TypeNameDescription
DRUGABI-007125 mg/m\^2 of ABI-007 administered by intravenously (IV) over 30 minutes on days 1, 8 and 15 of each 28 day cycle.
DRUGBevacizumabBevacizumab administered once every 2 weeks (10 mg/kg) by IV infusion after ABI-007 has been given. The first dose is one Day 1, cycle 1.

Timeline

Start date
2006-06-01
Primary completion
2009-09-01
Completion
2011-02-01
First posted
2006-10-31
Last updated
2019-11-25
Results posted
2013-05-22

Locations

20 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT00394082. Inclusion in this directory is not an endorsement.