Trials / Terminated
TerminatedNCT00386659
Immune Reconstitution in naïve HIV Patients With CD4 <100 Cells/mL When Treated With Lopinavir or Efavirenz.
A Randomized, Pilot Study on the Antiviral Activity and Immunological Effects of Lopinavir/Ritonavir vs. Efavirenz in Treatment-naïve HIV-Infected Patients With CD4 Cell Counts Below 100 Cells/mm3
- Status
- Terminated
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 60 (planned)
- Sponsor
- Hospital Clinic of Barcelona · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Pilot, randomized, parallel, open-label, controlled, clinical study evaluating virological response in plasma and extra-plasmatic compartments, together with the degree and kinetics of immune reconstitution in treatment-naïve patients with CD4 count below 100 cells/mL, when treated with tenofovir and abacavir together with lopinavir or efavirenz.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | tenofovir + abacavir + lopinavir/ritonavir | |
| DRUG | tenofovir + abacavir + efavirenz |
Timeline
- First posted
- 2006-10-11
- Last updated
- 2006-10-11
Locations
4 sites across 1 country: Spain
Source: ClinicalTrials.gov record NCT00386659. Inclusion in this directory is not an endorsement.