Trials / Completed
CompletedNCT00385957
Immunological and Viral Response to Antiretrovirals in HIV Patients With CD4 Cell Count Below 100
Comparison of Antiretroviral Activity and Immunological Effect of Two Triple Treatments With and Without Protease Inhibitors in naïve HIV-1-infected Patients With CD4 < 100/mm3
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 70 (planned)
- Sponsor
- Hospital Clinic of Barcelona · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The study analyzes the virological response in plasma and non-plasma compartments, as well as the degree and kinetics of immune reconstitution in 70 treatment-naive patients with CD4 \< 100/mm3, when they receive treatment with two nucleoside analogs (NRTI) plus one protease inhibitor (PI) compared with 2 NRTI plus one non-nucleoside (NNRTI).
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | AZT+3TC+IDV+RTV | |
| DRUG | AZT+3TC+EFV |
Timeline
- First posted
- 2006-10-11
- Last updated
- 2010-12-15
Locations
6 sites across 1 country: Spain
Source: ClinicalTrials.gov record NCT00385957. Inclusion in this directory is not an endorsement.