Clinical Trials Directory

Trials / Completed

CompletedNCT00385645

Atazanavir or Lopinavir in HIV Post-exposure Prophylaxis

Comparison of 2 Alternative Antiretroviral Combinations in HIV Post-exposure Prophylaxis: AZT-3TC (Combivir®) + Lopinavir-ritonavir (Kaletra®) Versus AZT-3TC (Combivir®)+ Atazanavir (Reyataz®). Multicentre, Prospective, Randomized, Open Study

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
255 (actual)
Sponsor
Hospital Clinic of Barcelona · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The study compares the adherence of 240 HIV-negative subjects randomly assigned to 2 different antiretroviral therapies for 28 days after accidental exposure to HIV.

Conditions

Interventions

TypeNameDescription
DRUGCombivir+Kaletra
DRUGCombivir+Reyataz

Timeline

Start date
2006-05-01
Primary completion
2009-08-01
Completion
2009-08-01
First posted
2006-10-11
Last updated
2010-03-31

Locations

7 sites across 1 country: Spain

Source: ClinicalTrials.gov record NCT00385645. Inclusion in this directory is not an endorsement.