Clinical Trials Directory

Trials / Completed

CompletedNCT00384423

Short Term Effects of PRX-03140 in Patients With Mild Alzheimer's Disease Being Treated With Aricept

A Randomized, Double-Blind, Placebo-Controlled, Phase IIa Study to Assess the Short-Term Effects of PRX-03140 Alone and in Combination With Donepezil in Subjects With Mild Alzheimer's Disease.

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
80 (estimated)
Sponsor
Epix Pharmaceuticals, Inc. · Industry
Sex
All
Age
60 Years
Healthy volunteers
Not accepted

Summary

This is a study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of PRX-03140 administered orally once daily for 14 days in subjects with mild Alzheimer's Disease who are using a stable, well-tolerated 10 mg dose of Aricept (donepezil) but continue to experience worsening AD symptoms.

Conditions

Interventions

TypeNameDescription
DRUGPRX-03140

Timeline

Start date
2006-10-01
Primary completion
2007-10-01
First posted
2006-10-06
Last updated
2008-01-30

Locations

17 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT00384423. Inclusion in this directory is not an endorsement.