Clinical Trials Directory

Trials / Completed

CompletedNCT00383149

A Phase II, Trial of Ixabepilone Plus Cetuximab as First Line Therapy for Metastatic Pancreatic Cancer

A Phase II, Open Label Trial of Ixabepilone Plus Cetuximab as First Line Therapy for Metastatic Pancreatic Cancer

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
58 (actual)
Sponsor
R-Pharm · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this clinical research study is to learn if ixabepilone plus cetuximab improves survival when given as 1st line chemotherapy in subjects with metastatic pancreatic cancer compared to historical data. The safety of this combination treatment will also be studied.

Conditions

Interventions

TypeNameDescription
DRUGIxabepiloneIntravenous Infusion (IV), 32 mg/m\^2 every 21 days.
DRUGCetuximabInitial dose of 400 mg/m\^2 intravenous (IV) over 2 hours) followed by a weekly lower dose of 250 mg/m\^2 IV over 1 hour.

Timeline

Start date
2007-01-01
Primary completion
2009-06-01
Completion
2009-06-01
First posted
2006-10-02
Last updated
2016-03-10
Results posted
2010-10-19

Locations

9 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT00383149. Inclusion in this directory is not an endorsement.

A Phase II, Trial of Ixabepilone Plus Cetuximab as First Line Therapy for Metastatic Pancreatic Cancer (NCT00383149) · Clinical Trials Directory