Trials / Completed
CompletedNCT00380939
This Study Uses Ultrasound to Determine Whether Atorvastatin or Pravastatin Effects the Progression of Coronary Plaque.
A Prospective, Randomized, Double-Blind, Multi-Center Study Comparing the Effects of Atorvastatin Versus Pravastatin on the Progression and Quantification of Coronary Atherosclerotic Lesions as Measured by Intravascular Ultrasound (REVERSAL)
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 600 (planned)
- Sponsor
- Pfizer · Industry
- Sex
- All
- Age
- 30 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
This study was designed to assess the effects on coronary artery plaque using aggressive lipid-lowering therapy versus moderate lipid-lowering therapy. A substudy will examine the effect of these treatments on brachial artery vasoactivity.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Atorvastatin | |
| DRUG | Pravastatin |
Timeline
- Start date
- 1999-04-01
- Completion
- 2000-12-01
- First posted
- 2006-09-27
- Last updated
- 2006-12-04
Locations
36 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT00380939. Inclusion in this directory is not an endorsement.