NCT00378456

Vitamins and Minerals for Children With Downs Syndrome

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: —
• Sponsor: Institute of Child Health · Academic / Other
• Sex: All
• Age: 0 Years – 7 Months
• Healthy volunteers: —

Summary

The trial aimed to examine the effects of supplementation with antioxidants and folinic acid on the health, growth and psychomotor development of children with Down syndrome. 156 children with Trisomy 21, less than 7 months of age were recruited and randomised into four groups to receive antioxidants, folinic acid, a combination of antioxidants and folinic acid or a placebo. Blinded outcome assessment was carried out 18 months later.Blood and urine samples were also taken around 12 months of age to examine metabolic effects of supplementation.

Conditions

• Trisiomy 21 (Down Syndrome)

Interventions

Type	Name	Description
DRUG	Antioxidants- (Vitamins A,C,E Selenium and Zinc)
DRUG	Folinic acid
DRUG	Vitamins A,C,E Selenium and Zinc and Folinic acid.
DRUG	Placebo

Timeline

• First posted: 2006-09-20
• Last updated: 2006-09-20

Locations

3 sites across 1 country: United Kingdom