Clinical Trials Directory

Trials / Completed

CompletedNCT00375427

Safety and Efficacy of Zoledronic Acid in Patients With Breast Cancer With Metastatic Bone Lesions

A Prospective, Randomized, Multi-center Comparative 2-arm Trial of Efficacy and Safety of Zoledronic Acid (Every 3-months vs. Every 4 Weeks) Beyond Approximately 1 Year of Treatment With Zoledronic Acid in Patients With Bone Lesions From Breast Cancer

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
430 (actual)
Sponsor
Novartis Pharmaceuticals · Industry
Sex
Female
Age
18 Years
Healthy volunteers
Not accepted

Summary

The objective of this study is to assess the clinical benefit of two different dosing schedules of zoledronic acid in patients with metastatic bone lesions from breast cancer who have already been treated with zoledronic acid for about one year.

Conditions

Interventions

TypeNameDescription
DRUGZoledronic acidZoledronic acid as a 15-minute (at least) intravenous (i.v.) infusion. The dose of study drug will be the same administered before the study entry, that is 4 mg or a reduced dose, i.e. 3.5 mg, or 3.3 mg or 3.0 mg.

Timeline

Start date
2006-02-01
Primary completion
2010-02-01
First posted
2006-09-13
Last updated
2012-04-11
Results posted
2011-08-04

Locations

1 site across 1 country: Italy

Source: ClinicalTrials.gov record NCT00375427. Inclusion in this directory is not an endorsement.