Trials / Completed
CompletedNCT00375245
Rapamycin With Grapefruit Juice for Advanced Malignancies
A Phase Ib Study Administering Rapamycin (Sirolimus) With Grapefruit Juice in Patients With Advanced Malignancies
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 41 (actual)
- Sponsor
- University of Chicago · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to determine the highest safe dose of rapamycin when given with a fixed amount of grapefruit juice.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Rapamycin (sirolimus) | Weekly oral doses, dose is assigned at the time of study entry |
| OTHER | Grapefruit Juice | Daily oral doses starting during the second week on study. |
Timeline
- Start date
- 2006-09-01
- Primary completion
- 2009-05-01
- Completion
- 2012-05-01
- First posted
- 2006-09-12
- Last updated
- 2014-01-17
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00375245. Inclusion in this directory is not an endorsement.