Trials / Unknown
UnknownNCT00373919
The Effect of Erythromycin on Occurrence of Leaks From Cervical Esophageal-Gastric Anastomosis After Trans-Hiatal Esophagectomy
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- —
- Sponsor
- Kaplan Medical Center · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Cervical anastomotic leak is one of the most common complications after trans-hiatal esophagectomy. Hypothesis: An early post operative administration of a pro-kinetic dosage of erythromycin will reduce leak occurrence. Design: This is a prospective, randomized, double blind, placebo controlled study. Number of patients: 30. Inclusion Criteria: * Patients after trans-hiatal esophagectomy Exclusion Criteria: * Allergy to erythromycin * Use of phenothiazine * QT prolongation * Liver function test (LFT) abnormalities * Myasthenia gravis * Cardiomyopathy
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | intravenous (IV) administration of erythromycin |
Timeline
- First posted
- 2006-09-08
- Last updated
- 2007-03-05
Source: ClinicalTrials.gov record NCT00373919. Inclusion in this directory is not an endorsement.