Trials / Completed
CompletedNCT00371566
A Study Of Lapatinib Versus Placebo Followed By Chemoradiation In Patients With Locally Advanced Head And Neck Cancer
A Randomized, Single Blinded, Placebo-controlled, Multi-centre, Phase II Study of Lapatinib in Patients With Locally Advanced Squamous Cell Carcinoma of the Head and Neck (SCCHN)
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 107 (actual)
- Sponsor
- GlaxoSmithKline · Industry
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This is a study comparing the activity of lapatinib versus placebo followed by chemoradiation. This study is designed to explore the effects of lapatinib monotherapy on apoptosis/necrosis, in pre-treatment and post-treatment tumour tissue samples in subjects with locally advanced squamous cell carcinoma of head and neck.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Lapatinib oral tablets | |
| DRUG | Placebo |
Timeline
- Start date
- 2006-03-01
- Primary completion
- 2007-12-01
- Completion
- 2007-12-01
- First posted
- 2006-09-04
- Last updated
- 2010-04-06
- Results posted
- 2010-01-29
Locations
9 sites across 5 countries: France, Greece, India, Peru, Spain
Source: ClinicalTrials.gov record NCT00371566. Inclusion in this directory is not an endorsement.