NCT00371319

Comparing the Efficacy of Tacrolimus and Mycophenolate Mofetil for the Initial Therapy of Active Lupus Nephritis

To Compare the Efficacy of Tacrolimus and Mycophenolate Mofetil for the Initial Therapy of Active Lupus Nephritis

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 150 (actual)
• Sponsor: Tuen Mun Hospital · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is comparing the efficacy of tacrolimus and mycophenolate mofetil for the initial therapy of active lupus glomerulonephritis.

Detailed description

Patients with biopsy proven active lupus nephritis will be randomized to receive tacrolimus or mycophenolate mofetil, on top of corticosteroids, for initial treatment. Efficacy and adverse effects will be compared.

Conditions

• Lupus Nephritis

Interventions

Type	Name	Description
DRUG	tacrolimus	0.06-0.1 mg/kg/day
DRUG	mycophenolate mofetil	2-3 gm/day

Timeline

• Start date: 2005-09-01
• Primary completion: 2014-05-01
• Completion: 2014-06-01
• First posted: 2006-09-04
• Last updated: 2014-07-02

Locations

1 site across 1 country: China