Clinical Trials Directory

Trials / Completed

CompletedNCT00370318

Prophylactic Antipyretic Treatment in Children Receiving Pneumococcal Conjugate and Standard Infant Vaccines

Multicentre Study to Assess the Effect of Prophylactic Antipyretic Treatment on the Rate of Febrile Reactions Following Concomitant Administration of GSK Biologicals' 10-valent Pneumococcal Conjugate, Infanrix Hexa and Rotarix Vaccines

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
400 (planned)
Sponsor
GlaxoSmithKline · Industry
Sex
All
Age
9 Weeks – 16 Weeks
Healthy volunteers
Accepted

Summary

The purpose of this trial is to assess if the rate of febrile reactions following the co-administration of pneumococcal conjugate vaccines with standard infant vaccines is lowered when paracetamol is given prophylactically.

Detailed description

2 groups (200 per group); control group receives no prophylactic antipyretic treatment.

Conditions

Interventions

TypeNameDescription
BIOLOGICAL10 valent pneumococcal conjugate vaccine
BIOLOGICALInfanrix Hexa
BIOLOGICALRotarix
DRUGParacetamol

Timeline

Start date
2006-09-01
Completion
2007-04-01
First posted
2006-08-31
Last updated
2017-03-23

Locations

10 sites across 1 country: Czechia

Source: ClinicalTrials.gov record NCT00370318. Inclusion in this directory is not an endorsement.