Clinical Trials Directory

Trials / Completed

CompletedNCT00369616

Efficacy and Safety of Nicotine-Qbeta Vaccine in Smokers

Evaluation of Efficacy and Safety of Nicotine-Qbeta (NicQb) Vaccine Versus Placebo in Healthy Smokers

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
341 (actual)
Sponsor
Cytos Biotechnology AG · Industry
Sex
All
Age
18 Years – 70 Years
Healthy volunteers

Summary

The purpose of this study is to help smokers quitting by vaccinating them with CYT002-NicQb. Upon vaccination, the smoker will generate antibodies directed against free nicotine. The antibodies will bind nicotine and prevent its passage into the brain. The successfully vaccinated smoker will have no reward effect after smoking, thus braking the vicious circle of nicotine addiction.

Conditions

Interventions

TypeNameDescription
BIOLOGICALCYT002-NicQb

Timeline

Start date
2003-12-01
Primary completion
2005-03-01
Completion
2005-10-01
First posted
2006-08-29
Last updated
2010-11-15

Locations

3 sites across 1 country: Switzerland

Source: ClinicalTrials.gov record NCT00369616. Inclusion in this directory is not an endorsement.