Clinical Trials Directory

Trials / Completed

CompletedNCT00369148

Combination of Glinides With Premixed Insulin

Evaluation of Usefulness of Combination Therapy of Rapid Acting Insulin Secretagogue (Glinide) With Premixed Insulin in Type 2 Diabetes

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
60 (planned)
Sponsor
Keio University · Academic / Other
Sex
All
Age
Healthy volunteers
Not accepted

Summary

Combination therapy of glinides with premixed insulin provides better glycemic control than premixed insulin alone.

Detailed description

Type 2 diabetic patients undergoing twice daily injections of premixed insulin are administered glinides (10mg of mitiglinide or 90 mg of nateglinide) at lunchtime without changing their insulin regimen. Twelve weeks after administration of the glinides, they are discontinued. HbA1c levels at the start of glinide administration, 12 weeks after administration, and 12 weeks after discontinuation are measured.

Conditions

Interventions

TypeNameDescription
DRUGnateglinide(drug) mitiglinide(drug)

Timeline

Start date
2004-07-01
Completion
2006-03-01
First posted
2006-08-29
Last updated
2009-08-26

Locations

6 sites across 1 country: Japan

Source: ClinicalTrials.gov record NCT00369148. Inclusion in this directory is not an endorsement.