NCT00368147

Access Creation for Hemodialysis: Association With Structural Changes of the Heart

Access Creation for Hemodialysis: Potential Contribution to Left Ventricular Remodelling

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 84 (actual)
• Sponsor: Ottawa Hospital Research Institute · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine if the creation of a fistula or a graft plays a role in the development of heart disease for patients undergoing hemodialysis

Detailed description

Patients with end stage renal disease are at 18-20 times greater risk of dying from cardiovascular disease as the general population. Both traditional and non-traditional cardiovascular risk factors are thought to be important. Of the non-tradtional cardiovascular risk factors, creation of an arteriovenous fistula or graft for the purposes of a blood access for hemodialysis may contribute to an elevation in BNP and left ventricular hypertrophy - both factors that have been associated with an increased risk of mortality Prior to access creation and at one month and one year post access creation - samples for BNP will be collected Prior to access creation and at one year post access creation - echocardiography will be performed

Conditions

• Arteriovenous Fistula
• Arteriovenous Graft
• Left Ventricular Hypertrophy
• Brain Natriuretic Peptide

Timeline

• Start date: 2002-04-01
• Completion: 2007-02-01
• First posted: 2006-08-24
• Last updated: 2023-11-13

Locations

1 site across 1 country: Canada