Trials / Completed
CompletedNCT00367224
Determining the Tolerance of Depigmented Skin to Targeted Phototherapy Using UVB in Patients With Vitiligo
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 17 (actual)
- Sponsor
- Henry Ford Health System · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
The purpose of this study is to determine if vitiligo patients develop tolerance to ultraviolet light therapy, a type of treatment available for vitiligo.
Detailed description
Patients with vitiligo received 6-9 ultraviolet B treatments, 2 to 3 times weekly. Minimal erythema dose (MED) testing was done at baseline and after all treatments; the percent change in MED was analysed as a measure of photoadaptation. The percent decrease in cyclobutane pyrimidine dimers (CPDs) over 24 hours after a single exposure of 1 MED was analysed on vitiliginous and normal skin.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | 6 to 9 ultraviolet B treatments | Treatments with ultraviolet B with gradually progressive doses |
| PROCEDURE | Skin biopsies | 4 mm punch biopsies of the skin |
Timeline
- Start date
- 2006-01-01
- Primary completion
- 2008-05-01
- Completion
- 2008-05-01
- First posted
- 2006-08-22
- Last updated
- 2024-04-30
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00367224. Inclusion in this directory is not an endorsement.