NCT00365950

3 Months' Versus 6 Months' Anticoagulation in Patients With DVT and/or PE

Clinical Trial of Two Durations of Warfarin Therapy in the Treatment of Deep Vein Thrombosis and/or Pulmonary Embolism

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 2,400 (planned)
• Sponsor: British Thoracic Society · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

To determine whether 3 months' anticoagulation is as good as or better than 6 months' for the treatment of DVT/PE

Detailed description

Multi-centre trial involving 46 hospitals in the United Kingdom, with patients entered by 137 Consultant Physicians. Consenting patients were randomised in a central office to either 3 months' or 6 months' anticoagulation. Information on progress of the patients was requested by the co-ordinating office at 3 months, 6 months and 12 months. Outcomes were measured as death from DVT/PE, non-fatal extensions or recurrences of DVT/PE and major haemorrhages during and after anticoagulation.

Conditions

• Deep Vein Thrombosis
• Pulmonary Embolism
• Deep Vein Thrombosis With Pulmonary Embolism

Interventions

Type	Name	Description
DRUG	Duration of anticoagulation
DRUG	Warfarin duration

Timeline

• Start date: 1999-09-01
• Completion: 2003-12-01
• First posted: 2006-08-18
• Last updated: 2006-08-18

Locations

2 sites across 1 country: United Kingdom