NCT00364494

Hemodilution and Outcome in Cardiac Surgery

Effect of Moderate Hemodilution During Cardiopulmonary Bypass on Postoperative Outcome Following Cardiac Surgery

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: —
• Sponsor: Università Vita-Salute San Raffaele · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

An hematocrit of 21-25% is supposed to perform the best organ protection during cardiopulmonary bypass for cardiac surgery. The investigators want to establish the best timing for a transfusion (in patients with a predicted low hematocrit during cardiopulmonary bypass) and the efficacy of preprocedural hemodilution (in patients with a predicted high hematocrit during cardiopulmonary bypass) in patients undergoing cardiac surgery.

Conditions

• Kidney Failure
• Intraoperative Complications

Interventions

Type	Name	Description
PROCEDURE	Different timing of red blood cells transfusion (substudy 1); Acute hemodilution versus no hemodilution (substudy 2)	Subgroup 1,with Ht\<21% receive an hemotransfusion before or after CEC;subgroup 2,with Ht\>25% bleed or not

Timeline

• Start date: 2006-11-01
• Primary completion: 2007-04-01
• Completion: 2007-04-01
• First posted: 2006-08-15
• Last updated: 2009-08-14

Locations

1 site across 1 country: Italy