Clinical Trials Directory

Trials / Unknown

UnknownNCT00363831

Combination of Capecitabine and Oxaliplatin in Metastatic Nasopharyngeal Carcinoma

A Multi-center Phase II Trial of Capecitabine in Combination With Oxaliplatin (Xelox) as First Line Chemotherapy in Patients With Metastatic Nasopharyngeal Carcinoma (NPC)

Status
Unknown
Phase
Phase 2
Study type
Interventional
Enrollment
42 (estimated)
Sponsor
The University of Hong Kong · Academic / Other
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

Primary: * To evaluate the efficacy of capecitabine in combination with oxaliplatin (XELOX) in terms of overall response rate (based on RECIST criteria) in patients with metastatic NPC without prior chemotherapy for relapse. Secondary: * To evaluate the efficacy profile of oxaliplatin (XELOX) in patients with metastatic NPC in terms of time to progression of disease, survival time, duration of response and complete response rate. * To study the safety and tolerability of the regimen in patients with metastatic NPC.

Conditions

Interventions

TypeNameDescription
DRUGOxaliplatin130mg/m² infusion day 1, repeat every 21 days

Timeline

Start date
2006-07-01
Primary completion
2009-12-01
First posted
2006-08-15
Last updated
2010-07-28

Locations

1 site across 1 country: Hong Kong

Source: ClinicalTrials.gov record NCT00363831. Inclusion in this directory is not an endorsement.